Problems with Repitier 92: please see errors

The COMM port is shown in an attachment.
No errors during compile.
Errors appear when installing.

Any help appreciated.

Arduino: 1.8.5 (Windows 10), Board: "Arduino/Genuino Mega or Mega 2560, ATmega2560 (Mega 2560)"

Sketch uses 110426 bytes (43%) of program storage space. Maximum is 253952 bytes.
Global variables use 4040 bytes (49%) of dynamic memory, leaving 4152 bytes for local variables. Maximum is 8192 bytes.
avrdude: ser_open(): can't open device "\\.\COM4": The system cannot find the file specified.


avrdude: ser_drain(): read error: The handle is invalid.


avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
the selected serial port
does not exist or your board is not connected
avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: ser_send(): write error: sorry no info avail
avrdude: stk500_send(): failed to send command to serial port
avrdude: ser_recv(): read error: The handle is invalid.


avrdude: stk500v2_ReceiveMessage(): timeout
avrdude: stk500v2_getsync(): timeout communicating with programmer

This report would have more information with
"Show verbose output during compilation"
option enabled in File -> Preferences.

Do you see the big yellow exclamation mark on the device?

that means windows has ****** up, and that device does not currently work.

You cannot expect other software to be able to access the device when the operating system hasn't set it up correctly.

You probably need to install device drivers

What device drivers are needed?, this depends on your contoller board
If its a Chinese clone board probably ch340 drivers download here [www.wch.cn]
or perhaps ftdi drivers, download from here [www.ftdichip.com]