Which mode are you running the TMC2208 drivers in? They are generally quieter in Stealthchop 2 mode than in spread cycle mode. If you are using spread cycle mode and they are noisy at standstill, reducing the TOFF parameter in the chopper configuration register may help.
Changes in supply voltage, configured motor current and motor inductance all affect the amount of noise produced.
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Disclosure: I design Duet electronics and work on RepRapFirmware, [duet3d.com].