Disable skeiniso and skeinlayer.
If you want to preview layers you should enable output penultimate gcode in export and open that file afterwards from skeinlayer.
Most of the time disabling skeiniso is sufficient but as you say that the skein takes long be safe.
Manufacturer of low tolerance Filaments PLA, ABS, ASA, PETG, TPU, PA, PVA,
[
www.miafilament.com]
[
github.com]