I have my ini file in a shared location so I use with slic3r on different machines. Currently I start it with --load and --autosave parameters, but I get strange presets created of type slic3r.ini (modified) when I start up. Is this expected?

So looking into this more, it seems that the profiles are not saved like this and are saved in an local directory as specified by wxWidgets. So will need to keep looking, or submit a feature request.